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Serum neuron-specific enolase concentrations as a predictor of mortality in children with traumatic brain injury

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00052216" target="_blank" >RIV/00216224:14110/11:00052216 - isvavai.cz</a>

  • Alternative codes found

    RIV/65269705:_____/11:#0001400

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Serum neuron-specific enolase concentrations as a predictor of mortality in children with traumatic brain injury

  • Original language description

    The aims of this study were the correlations of neuron-specific enolase (NSE) serum levels and mortality, Glasgow Outcome Scale (GOS) and lenght of hospitalization in children with traumatic brain injury (TBI). Material and method: The study protocol andinformed consent were approved by the ethics committee of University Hospital Brno. During the period from May 2007 to October 2009 sixty-three patients with TBI were enrolled into the prospective study. TBI was verified by computerized tomography. Venous blood samples were taken after admission and every 24 h for a maximum of 6 consecutive days. Serum concentrations of neuron-specific enolase were quantified immuno-luminometrically. Six months after the primary injury, the study protocol documented outcome according to the Glasgow Outcome Score. Results: NSE values is significantly higher in patients who died compared to patients who survived.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FG - Paediatrics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Česko-slovenská pediatrie

  • ISSN

    0069-2328

  • e-ISSN

  • Volume of the periodical

    66

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    7

  • Pages from-to

    68-74

  • UT code for WoS article

  • EID of the result in the Scopus database