Dynamics of Glial Fibrillary Acidic Protein During Traumatic Brain Injury in Children

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F11%3A00055261" target="_blank" >RIV/00216224:14110/11:00055261 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/11:#0001230
Result on the web
<a href="http://dx.doi.org/10.1097/TA.0b013e3182140c8c" target="_blank" >http://dx.doi.org/10.1097/TA.0b013e3182140c8c</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/TA.0b013e3182140c8c" target="_blank" >10.1097/TA.0b013e3182140c8c</a>

Result language
angličtina
Original language name
Dynamics of Glial Fibrillary Acidic Protein During Traumatic Brain Injury in Children
Original language description
Backgrounds: Glial fibrillary acidic protein (GFAP) is a monomeric intermediate filament protein found in the astroglial cytoskeleton and is not found outside the central nervous system. It is a brain-specific protein that is released after traumatic brain injury (TBI). Methods: This prospective study enrolled 59 children who had TBI, as verified by computed tomography. Daily GFAP measurement began at admission (< 12 hours after trauma) and continued for 6 days. Blood samples were analyzed for GFAP by enzyme-linked immunosorbent assay. Outcome was assessed using the Glasgow Outcome Scale (GOS) at 6 months after injury. Results: The median serum levels of GFAP at admission were 7.47 ng/mL in patients who died, compared with 0.12 ng/mL in patients whosurvived (p = 0.002). GFAP levels were significantly higher in patients who had a poor outcome 6 months after injury than in those who were alive or had good outcome (p < 0.001).
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical
The Journal of Trauma: Injury, Infection and Critical Care
ISSN
0022-5282
e-ISSN
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Volume of the periodical
71
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
854-859
UT code for WoS article
000295925700020
EID of the result in the Scopus database
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