Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohorts

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00059972" target="_blank" >RIV/00216224:14110/12:00059972 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/12:8038 RIV/00064203:_____/12:8038

Result on the web

<a href="http://dx.doi.org/10.1016/S1470-2045(11)70299-6" target="_blank" >http://dx.doi.org/10.1016/S1470-2045(11)70299-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/S1470-2045(11)70299-6" target="_blank" >10.1016/S1470-2045(11)70299-6</a>

Result language

angličtina

Original language name

Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohorts

Original language description

The risk of recurrence of gastrointestinal stromal tumour (GIST) after surgery needs to be estimated when considering adjuvant systemic therapy. We assessed prognostic factors of patients with operable GIST, to compare widely used risk-stratification schemes and to develop a new method for risk estimation. Methods Population-based cohorts of patients diagnosed with operable GIST, who were not given adjuvant therapy, were identified from the literature. Data from ten series and 2560 patients were pooled.Risk of tumour recurrence was stratified using the National Institute of Health (NIH) consensus criteria, the modified consensus criteria, and the Armed Forces Institute of Pathology (AFIP) criteria. Prognostic factors were examined using proportional hazards and non-linear models. The results were validated in an independent centre-based cohort consisting of 920 patients with GIST. Findings Estimated 15-year recurrence-free survival (RFS) after surgery was 59.9% (95% CI 56.2-63.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Lancet Oncology

ISSN

1470-2045

e-ISSN

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Volume of the periodical

13

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

265-274

UT code for WoS article

000300880600034

EID of the result in the Scopus database

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