Mammalian metallothioneins: properties and functions

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00060504" target="_blank" >RIV/00216224:14110/12:00060504 - isvavai.cz</a>
Alternative codes found
RIV/62156489:43210/12:00189920 RIV/00216305:26620/12:PU99322 RIV/00216208:11310/12:10126294 RIV/00216208:11130/12:8202 and 2 more
Result on the web
<a href="http://dx.doi.org/10.1039/c2mt20081c" target="_blank" >http://dx.doi.org/10.1039/c2mt20081c</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c2mt20081c" target="_blank" >10.1039/c2mt20081c</a>

Result language
angličtina
Original language name
Mammalian metallothioneins: properties and functions
Original language description
Metallothioneins (MT) are a family of ubiquitous proteins, whose role is still discussed in numerous papers, but their affinity to some metal ions is undisputable. These cysteine-rich proteins are connected with antioxidant activity and protective effects on biomolecules against free radicals, especially reactive oxygen species. In this review, the connection between zinc(II) ions, reactive oxygen species, heavy metal ions and metallothioneins is demonstrated with respect to effect of these proteins oncell proliferation and a possible negative role in resistance to heavy metal-based and non-heavy metal-based drugs.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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