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Mammalian metallothioneins: properties and functions

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00060504" target="_blank" >RIV/00216224:14110/12:00060504 - isvavai.cz</a>

  • Alternative codes found

    RIV/62156489:43210/12:00189920 RIV/00216305:26620/12:PU99322 RIV/00216208:11310/12:10126294 RIV/00216208:11130/12:8202 and 2 more

  • Result on the web

    <a href="http://dx.doi.org/10.1039/c2mt20081c" target="_blank" >http://dx.doi.org/10.1039/c2mt20081c</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1039/c2mt20081c" target="_blank" >10.1039/c2mt20081c</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Mammalian metallothioneins: properties and functions

  • Original language description

    Metallothioneins (MT) are a family of ubiquitous proteins, whose role is still discussed in numerous papers, but their affinity to some metal ions is undisputable. These cysteine-rich proteins are connected with antioxidant activity and protective effects on biomolecules against free radicals, especially reactive oxygen species. In this review, the connection between zinc(II) ions, reactive oxygen species, heavy metal ions and metallothioneins is demonstrated with respect to effect of these proteins oncell proliferation and a possible negative role in resistance to heavy metal-based and non-heavy metal-based drugs.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Metallomics

  • ISSN

    1756-5901

  • e-ISSN

  • Volume of the periodical

    4

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    12

  • Pages from-to

    739-750

  • UT code for WoS article

  • EID of the result in the Scopus database