Functional neuroanatomy of vocalization in patients with Parkinson's disease

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00068876" target="_blank" >RIV/00216224:14110/12:00068876 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.jns.2011.10.020" target="_blank" >http://dx.doi.org/10.1016/j.jns.2011.10.020</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jns.2011.10.020" target="_blank" >10.1016/j.jns.2011.10.020</a>

Result language
angličtina
Original language name
Functional neuroanatomy of vocalization in patients with Parkinson's disease
Original language description
In Parkinson's disease (PD) both speech production and self-monitoring of voiced speech are altered. Methods: In our previous study we used functional magnetic resonance imaging (fMRI) to examine which brain areas are involved in overt reading in nine female PD patients (mean age 66.0 +/- 11.6 years) compared with eight age-matched healthy female controls (mean age 62.2 years +/- 12.3). Here we performed the posthoc seed-based functional connectivity analysis of our data to assess the functional connectivity between the periaqueductal gray matter (PAG; i.e. the core subcortical structure involved in human vocalization) and other brain regions in the same groups of PD patients and controls. Results: In PD patients as compared with controls we observed increased connectivity between PAG and basal ganglia, posterior superior temporal gyrus, supramarginal and fusiform gyri and inferior parietal lobule on the right side.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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