Genetics of anti-EHV antibody responses in a horse population

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00068374" target="_blank" >RIV/00216224:14110/13:00068374 - isvavai.cz</a>

Alternative codes found

RIV/62157124:16170/13:43872343 RIV/62157124:16810/13:43872343 RIV/62156489:43210/13:00200266

Result on the web

<a href="http://dx.doi.org/10.1016/j.rvsc.2013.03.011" target="_blank" >http://dx.doi.org/10.1016/j.rvsc.2013.03.011</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.rvsc.2013.03.011" target="_blank" >10.1016/j.rvsc.2013.03.011</a>

Result language

angličtina

Original language name

Genetics of anti-EHV antibody responses in a horse population

Original language description

Individual variation in immune responses to herpesviruses was observed in various species. Here, associations between polymorphic molecular markers and life-long anti-EHV-1/4 antibody immune responses were analyzed in a model EHV-infected population of the Old Kladruber horses. Two-dimensional analysis including overall mean titers and titer dynamics expressed by differences between spring and autumn titers allowed identification of low-responders. 50 randomly selected microsatellites and nine single nucleotide polymorphisms in nine immunity-related candidate genes were genotyped. Due to differences (p&lt;0.001) in antibody titers between two color varieties of Old Kladruber horses, separate association studies were performed in the two sub-populationsby using the Fisher's exact test. In black horses, the interleukin 4 receptor and MxA protein coding genes, and the microsatellite TKY325 were associated with the responder status.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Research in Veterinary Sciences

ISSN

0034-5288

e-ISSN

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Volume of the periodical

Vol. 95

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

6

Pages from-to

137-142

UT code for WoS article

000320289600022

EID of the result in the Scopus database

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