The effect of spironolactone in patients with resistant arterial hypertension in relation to baseline blood pressure and secondary causes of hypertension

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00072692" target="_blank" >RIV/00216224:14110/13:00072692 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/13:33147522 RIV/00098892:_____/13:#0000563

Result on the web

<a href="http://dx.doi.org/10.5507/bp.2012.078" target="_blank" >http://dx.doi.org/10.5507/bp.2012.078</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2012.078" target="_blank" >10.5507/bp.2012.078</a>

Result language

angličtina

Original language name

The effect of spironolactone in patients with resistant arterial hypertension in relation to baseline blood pressure and secondary causes of hypertension

Original language description

Aims. There are currently limited data about whether the effect of spironolactone in patients with resistant arterial hypertension depends on baseline blood pressure and the presence of a secondary cause of hypertension. Methods. Patients with office systolic blood pressure (BP) &gt; 140 mmHg or diastolic BP &gt; 90 mmHg, despite treatment with at least 3 antihypertensive drugs including a diuretic, were randomly assigned to receive spironolactone or a placebo for 8 weeks in a double-blind, placebo-controlled, multicentre trial (ASPIRANT). Results. Analyses were done with 55 patients treated with spironolactone. The degree of BP reduction after 8 weeks of spironolactone treatment did not differ significantly between the three tertiles of baseline systolic BP and patients with and without a secondary cause of hypertension. The reduction of office systolic, office diastolic BP and office pulse pressure was significantly lower in the highest tertile with baseline diastolic BP &gt; 97 mmHg

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers, Olomouc: Palacky University

ISSN

1213-8118

e-ISSN

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Volume of the periodical

157

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

50-55

UT code for WoS article

000316989100009

EID of the result in the Scopus database

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