Antitumour activities of sanguinarine and related alkaloids

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00074837" target="_blank" >RIV/00216224:14110/14:00074837 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s11101-013-9290-8" target="_blank" >http://dx.doi.org/10.1007/s11101-013-9290-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11101-013-9290-8" target="_blank" >10.1007/s11101-013-9290-8</a>

Result language
angličtina
Original language name
Antitumour activities of sanguinarine and related alkaloids
Original language description
Sanguinarine is a best-known member of a relatively small group of quaternary benzo[c]phenanthridine alkaloids (QBAs). QBAs are widely distributed in the family Papaveraceae and, to a limited extent, in some species of the families Fumariaceae and Rutaceae. From a medical perspective, QBAs have many important properties. In addition to antitumour activity, they display antimicrobial, antifungal and anti-inflammatory effects. They may interact with many targets, such as DNA and microtubules, and they modify the activities of a wide variety of enzymes. This review summarises the current state of knowledge about the properties of QBAs that are important for their potential use in anticancer therapy.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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