Quaternary benzo[c]phenanthridine alkaloids biological activities.Intracellular targets of their action and application in human and veterinary medicine.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F03%3A25033090" target="_blank" >RIV/68081715:_____/03:25033090 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Quaternary benzo[c]phenanthridine alkaloids biological activities.Intracellular targets of their action and application in human and veterinary medicine.
Original language description
The article briefly reviewes information on the occurence of of benzo[c]phenanthridine alkaloids (QBA) in plats and on their chemical properties important from the viewpoint of QBA biological and biochemical activities. Than recent results of investigation of authors on QBA are presented: 1. Identification of chemical forms of sanguinarine and cheleryhtrine that complex with mercapto nuclophiles and the determination of stability constants that characterize their binding with human serum albumin;2. Inhibition effects of sanguinarine, cheleryhtrine and fagaronine on DPP-IV-like enzymes isolated from blood plasma and human and rat glinoma cell lines; and 3. QBA role in the genesis of epidemic dropsy syndrome.
Czech name
—
Czech description
—
Classification
Type
C - Chapter in a specialist book
CEP classification
CE - Biochemistry
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/GA203%2F02%2F0023" target="_blank" >GA203/02/0023: Development of new procedures for highly reliable analytical control of technologies,materials,food &environment & for med. diagnostic using modern instrumentat</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Chemical Probes in Biology. Science at the Interface of Chemistry, Biology and Medicine. NATO Science Series, II. Mathematics, Physics and Chemistry, Vol. 129.
ISBN
1-4020-1769-3
Number of pages of the result
9
Pages from-to
245-254
Number of pages of the book
—
Publisher name
Kluwer Academic Publishers
Place of publication
Dordrecht
UT code for WoS chapter
—