Trefoil factor 3 as a marker of intestinal cell damage during sepsis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00082863" target="_blank" >RIV/00216224:14110/15:00082863 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/15:00064084
Result on the web
<a href="http://dx.doi.org/10.1515/med-2015-0020" target="_blank" >http://dx.doi.org/10.1515/med-2015-0020</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1515/med-2015-0020" target="_blank" >10.1515/med-2015-0020</a>
Alternative languages
Result language
angličtina
Original language name
Trefoil factor 3 as a marker of intestinal cell damage during sepsis
Original language description
Objective: Gastrointestinal dysfunction or gut failure frequently occurs in seriously ill patients and can be responsible for multi-organ failure. Trefoil factor 3 (TFF3) was characterized for its role in reconstitution of an epithelial barrier after mucosal injury in the jejunum. The aims of our study was an analysis of TFF3 levels dynamics in patients with sepsis and the correlation of TFF3 with severity of sepsis and mortality. Methods: Prospective observational study, a ten days evaluation period inchildren aged 0-19 years with systemic inflammatory response syndrome or septic state. Blood tests to determine levels of TFF3 were obtained as long as the patient met the criteria for systemic inflammatory response syndrome or sepsis. Results: Analysisof dynamics revealed steady levels of TFF3 during the 10 day period evaluated. TFF3 levels could not differentiate between various septic conditions in patients until a marked organ dysfunction developed.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FG - Paediatrics
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Open Medicine
ISSN
2391-5463
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
1
Country of publishing house
PL - POLAND
Number of pages
6
Pages from-to
261-266
UT code for WoS article
000371696900021
EID of the result in the Scopus database
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