Comparison of sublingual isosorbide dinitrate and Valsalva maneuver for detection of obstruction in hypertrophic cardiomyopathy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00085177" target="_blank" >RIV/00216224:14110/15:00085177 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/15:00062953 RIV/00216208:11130/15:10315675 RIV/00064203:_____/15:10315675

Result on the web

<a href="http://dx.doi.org/10.5114/aoms.2015.47096" target="_blank" >http://dx.doi.org/10.5114/aoms.2015.47096</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5114/aoms.2015.47096" target="_blank" >10.5114/aoms.2015.47096</a>

Result language

angličtina

Original language name

Comparison of sublingual isosorbide dinitrate and Valsalva maneuver for detection of obstruction in hypertrophic cardiomyopathy

Original language description

Introduction: A left ventricular outflow tract (LVOT) obstruction assessment with a provoking test should be a routine part of the evaluation of patients with hypertrophic cardiomyopathy (HCM). The aim of this study was to compare the utility of the Valsalva maneuver (VM) and sublingual spray application of isosorbide dinitrate (ISDN) for detection of an obstruction. Material and methods: We prospectively evaluated 81 consecutive HCM patients without severe rest LVOT obstruction (defined as peak rest pressure gradient (PG) &gt;= 50 mm Hg). We measured PG at rest, during the VM, after sublingual ISDN spray, and during the VM after ISDN. An obstruction was defined as a PG &gt;= 30 mm Hg. Results: An obstruction was present in 15 patients (19%) at rest (median and interquartile range of PG 16 (7-26) mm Hg), in 38 patients (47%) during the VM (PG 28 (12-49) mm Hg), in 50 (62%) patients after ISDN (PG 50 (12-79) mm Hg), and in 55 patients (68%) during the VM after ISDN (PG 59 (20-87) mm Hg)

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Archives of Medical Science

ISSN

1734-1922

e-ISSN

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Volume of the periodical

11

Issue of the periodical within the volume

4

Country of publishing house

PL - POLAND

Number of pages

5

Pages from-to

751-755

UT code for WoS article

000359484900007

EID of the result in the Scopus database

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