Serum tenascin-C discriminates patients with active SLE from inactive patients and healthy controls and predicts the need to escalate immunosuppressive therapy: a cohort study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00085323" target="_blank" >RIV/00216224:14110/15:00085323 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/15:10313606 RIV/00023728:_____/15:#0005068

Result on the web

<a href="http://dx.doi.org/10.1186/s13075-015-0862-4" target="_blank" >http://dx.doi.org/10.1186/s13075-015-0862-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s13075-015-0862-4" target="_blank" >10.1186/s13075-015-0862-4</a>

Result language

angličtina

Original language name

Serum tenascin-C discriminates patients with active SLE from inactive patients and healthy controls and predicts the need to escalate immunosuppressive therapy: a cohort study

Original language description

Introduction: The aim of this study was to examine whether circulating levels of the proinflammatory glycoprotein tenascin-C (TNC) are useful as an activity-specific or predictive biomarker in systemic lupus erythematosus (SLE). Methods: Serum TNC levelswere determined by enzyme-linked immunosorbent assay at inception visit in a prospective cohort of 59 SLE patients, and in 65 healthy controls (HC). SLE patients were followed for a mean of 11 months, disease activity was assessed using the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2 K) and British Isles Lupus Assessment Group disease activity index (BILAG-2004), clinical and laboratory data were recorded every 3-6 months, and changes in glucocorticoids (GC) and immunosuppressants (IS) were recorded serially.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

<a href="/en/project/NT13707" target="_blank" >NT13707: Evaluation of new laboratory markers correlated with dynamic clinical monitorning of of patients with Systemic Lupus Erythematosus (SLE) from SLE inception cohort from 2 academic centers</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Arthritis Research & Therapy

ISSN

1478-6354

e-ISSN

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Volume of the periodical

17

Issue of the periodical within the volume

341

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

1-11

UT code for WoS article

000365253400002

EID of the result in the Scopus database

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