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Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F18%3A00102274" target="_blank" >RIV/00216224:14110/18:00102274 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.brainresbull.2018.01.015" target="_blank" >http://dx.doi.org/10.1016/j.brainresbull.2018.01.015</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.brainresbull.2018.01.015" target="_blank" >10.1016/j.brainresbull.2018.01.015</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Principles of Diffusion Kurtosis Imaging and its Role in Early Diagnosis of Neurodegenerative Disorders

  • Original language description

    Pathology of neurodegenerative diseases can be correlated with intra-neuronal as well as extracellular changes which lead to neuronal degeneration. The central nervous system (CNS) is a complex structure comprising of many biological barriers. These microstructural barriers might be affected by a variety of pathological processes. Specifically, changes in the brain tissue’s microstructure affect the diffusion of water which can be assessed non-invasively by diffusion weighted (DW) magnetic resonance imaging (MRI) techniques. Hence, the purpose of this article is to summarize the ongoing clinical and preclinical research on Parkinson’s, Alzheimer’s and Huntington diseases, using DKI and to discuss the role of this technique as an early stage biomarker of neurodegenerative conditions.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Brain Research Bulletin

  • ISSN

    0361-9230

  • e-ISSN

  • Volume of the periodical

    139

  • Issue of the periodical within the volume

    MAY 2018

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    91-98

  • UT code for WoS article

    000433651600011

  • EID of the result in the Scopus database

    2-s2.0-85044387311