Phosphorylation at the Helm: Kinase-Mediated Regulation of Primary Cilia Assembly and Disassembly
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F25%3A00144585" target="_blank" >RIV/00216224:14110/25:00144585 - isvavai.cz</a>
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/cm.22012" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/cm.22012</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/cm.22012" target="_blank" >10.1002/cm.22012</a>
Alternative languages
Result language
angličtina
Original language name
Phosphorylation at the Helm: Kinase-Mediated Regulation of Primary Cilia Assembly and Disassembly
Original language description
The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying this control still awaits full resolution. Through their enzymatic activity, kinases function as flexible yet highly controllable regulators of a vast variety of cellular processes. Their activity ranges from cell cycle control to regulation of cell motility, signal transduction, and metabolism. This review focuses on the emerging role of kinases in primary cilia biology. We underscore their functions in primary cilia formation, maintenance, and resorption while examining available models and the respective mechanisms of their actions.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10601 - Cell biology
Result continuities
Project
<a href="/en/project/GA22-13277S" target="_blank" >GA22-13277S: Cilia-related Tau tubulin kinase 2 in health and disease: structure and function</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
CYTOSKELETON
ISSN
1949-3584
e-ISSN
1949-3592
Volume of the periodical
82
Issue of the periodical within the volume
11
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
707-718
UT code for WoS article
001519216000001
EID of the result in the Scopus database
2-s2.0-86000500918