EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROUSSOFLAVONOL B IN A MODEL OF INDUCED PLANTAR EDEMA IN LABORATORY MICE
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F25%3A00144404" target="_blank" >RIV/00216224:14160/25:00144404 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
EVALUATION OF THE ANTI-INFLAMMATORY ACTIVITY OF BROUSSOFLAVONOL B IN A MODEL OF INDUCED PLANTAR EDEMA IN LABORATORY MICE
Original language description
Prenylated phenols are natural substances that are used in traditional medicine for their wide range of biological effects. Broussoflavonol B was isolated from Broussonetia papyrifera with various biological activities, such as antioxidant, and anti-inflammatory activity. The anti-inflammatory activity of broussoflavonol B has been described in vitro, and inhibition of NF-κB and IL-1β activity has been demonstrated. The next step in the investigation of the biological activity of these natural compounds is to verify their anti-inflammatory potential in vivo. The experiment follows the previous in vitro research phases, which confirmed the anti-inflammatory activity of the selected natural substances.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30500 - Other medical sciences
Result continuities
Project
<a href="/en/project/GA23-04655S" target="_blank" >GA23-04655S: Role of prenylation and glycosylation patterns in anti-inflammatory activity and metabolism of natural phenolic compounds</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů