Crystal structure of CV-IIL lectin from human opportunistic pathogen

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F05%3A00013841" target="_blank" >RIV/00216224:14310/05:00013841 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Crystal structure of CV-IIL lectin from human opportunistic pathogen

Original language description

Carbohydrates are essential components of life that play crucial role in all organisms. They are very important agent in recognition and signalling ways. Lectin-carbohydrate interactions play a crucial role in many recognition events. Chromobacterium violaceum is a gram-negative bacterium first described at the end of 19th century. This bacterium has been found in tropical and subtropical regions, water and borders of the Negro river. Ch. violaceum is an opportunistic pathogen and may cause diseases inimmunocompromised individuals [1]. It is phylogenetically related with human pathogen Pseudomonas aeruginosa, which produces PA-IIL lectin, closely related with its virulence. The contribution is focused on identification and structure-function characterisation of PA-IIL homolog, CV-IIL, found by searching in sequenced bacterial genome of Ch. violaceum [2] The gene of the protein has been cloned and resulting protein CV-IIL has been purified by affinity chromatography. CV-IIL/-methyl-D-m

Czech name

Krystalová struktura lektinu CV-IIL z lidského podmíněného patogenu

Czech description

Carbohydrates are essential components of life that play crucial role in all organisms. They are very important agent in recognition and signalling ways. Lectin-carbohydrate interactions play a crucial role in many recognition events. Chromobacterium violaceum is a gram-negative bacterium first described at the end of 19th century. This bacterium has been found in tropical and subtropical regions, water and borders of the Negro river. Ch. violaceum is an opportunistic pathogen and may cause diseases inimmunocompromised individuals [1]. It is phylogenetically related with human pathogen Pseudomonas aeruginosa, which produces PA-IIL lectin, closely related with its virulence. The contribution is focused on identification and structure-function characterisation of PA-IIL homolog, CV-IIL, found by searching in sequenced bacterial genome of Ch. violaceum [2] The gene of the protein has been cloned and resulting protein CV-IIL has been purified by affinity chromatography. CV-IIL/-methyl-D-m

Type

D - Article in proceedings

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Materials Structure in Chemistry, Biology, Physics and Technology

ISBN

1211-5894

ISSN

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e-ISSN

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Number of pages

1

Pages from-to

148-149

Publisher name

Krystalograficka spolecnost

Place of publication

Praha

Event location

Trest

Event date

Jun 20, 2005

Type of event by nationality

CST - Celostátní akce

UT code for WoS article

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