THE ASSOCIATION OF IL-6 GENE POLYMORPHISM WITH ADHD IN CHILDREN

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F05%3A00015217" target="_blank" >RIV/00216224:14310/05:00015217 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
THE ASSOCIATION OF IL-6 GENE POLYMORPHISM WITH ADHD IN CHILDREN
Original language description
Attention-deficit hyperactivity disorder (ADHD) is a common neurodevelopmental polygenetic heritable disorder that includes inattention, excessive motor activity, impulsivity and distractibility. In the past few years, interest in the molecular geneticsof ADHD has grown enormously, with many groups searching for susceptibility genes. Dopaminergic genes have been prime candidates in the search for the genetic factors underlying novelty seeking because of the central role that dopamine plays in the brain's reward system. However, the findings are not conclusive and other new polymorphisms in different gene backgrounds are investigated. We have investigated whether there is an association between genes involving nervous system - cytokines, including IL-2, IL-6, and tumor necrosis factor-alpha (TNF-alpha). It is known that proinflammatory pleiotropic cytokines such as interleukin-6 (IL-6) are expressed in the central nervous system (CNS) during disease conditions and affect several brain
Czech name
Asociace polymorfizmu genu pro IL-6 s ADHD u dětí
Czech description
Zkoumali jsme vztah mezi ADHD a polymorfizmem genu pro IL-6 na souboru hyperkinetických chlapců. Zjistili jsme vztah mezi tímto polymorfizmem a ADHD.

Project
<a href="/en/project/NF6520" target="_blank" >NF6520: Clinical and molecular-biological correlates of attention deficit hyperactivity disorder in children</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2005
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
IX. Pracovní setkání biochemiků a molekulárních biologů
ISBN
80-210-3635-4
ISSN
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e-ISSN
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Number of pages
2
Pages from-to
29-30
Publisher name
Masarykova univerzita v Brně
Place of publication
Brno
Event location
Konferenční centrum ÚSKM Vinařská v Brně
Event date
Jan 1, 2005
Type of event by nationality
CST - Celostátní akce
UT code for WoS article
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