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Preparation and cis-to-trans transformation study of square-planar [Pt(L-n)2Cl(2)] complexes bearing cytokinins derived from 6-benzylaminopurine (L-n) by view of NMR spectroscopy and X-ray crystallography

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F08%3A00027229" target="_blank" >RIV/00216224:14310/08:00027229 - isvavai.cz</a>

  • Alternative codes found

    RIV/61389030:_____/08:00322106 RIV/61989592:15310/08:00005558

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Preparation and cis-to-trans transformation study of square-planar [Pt(L-n)2Cl(2)] complexes bearing cytokinins derived from 6-benzylaminopurine (L-n) by view of NMR spectroscopy and X-ray crystallography

  • Original language description

    Mononuclear, square-planar platinum(II) complexes involving derivatives of aromatic cytokinins as the ligands, and having the general formula cis-[Pt(L-n)(2)Cl-2] (1-3) and trans-[Pt(L-n)(2)Cl-2] (4-6), where n = 13, L-1 = 2-chloro-6-(benzylamino)-9-isopropylpurine, L-2 = 2-chloro-6-[(4-methoxybenzyl)amino]-9-isopropylpurine and L-3 = 2-chloro-6-[(2-methoxybenzyl)-amino]-9-isopropylpurine, have been synthesized and characterized by elemental analysis, MALDI-TOF mass, FT IR, H-1, C-13, N-15 and Pt-195 NMR spectral measurements. Dynamic cis-to-trans isomerization process of complex 1 in N,N'-dimethylformamide (DMF) has been investigated by means of multinuclear NMR spectroscopy. The solid-state structures of 1, 4 center dot (DMF)(2), and 5 have been determined by single crystal X-ray analysis. X-ray structures revealed that the heterocyclic ligands are coordinated to platinum via nitrogen atom N(7) in all the complexes studied. In vitro cytotoxicity of the prepared complexes against MCF7

  • Czech name

    Příprava a cis-trans transformace čtvercově-planárních platnatých komplexů s benzylaminopurinovými cytokininy očima NMR spektroskopie a RTG strukturní analýzy

  • Czech description

    V práci byly studovány čtvercově planární platnaté komplexy s aromatickými cytokininy jako ligandy metodami MALDI, FTR a multijadernou NMR. U vybraných - krystalizovatelných - komplexů byly určeny i jejich 3D krystalové struktury.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CA - Inorganic chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Polyhedron

  • ISSN

    0277-5387

  • e-ISSN

  • Volume of the periodical

    27

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    11

  • Pages from-to

  • UT code for WoS article

    000258616400029

  • EID of the result in the Scopus database