Exploring the 3D structure of the N-acetylglucosaminyltransferase V
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F09%3A00039160" target="_blank" >RIV/00216224:14310/09:00039160 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Exploring the 3D structure of the N-acetylglucosaminyltransferase V
Original language description
In the present study, we have attempted to build model of the GnT-V 3D-structure. Unfortunately, it is not clear to which GT family GnT-V belongs, therefore, we used one structure from the GT-A family and one structure from the GT-B one as structure templates. Selected structures had the best primary sequence alignment with GnT-V minimal catalytic domain. We have chosen structure of Core2 transferase (2GAM) as the representative of the GT-A family and MurG transferase (1NLM) as the representative of theGT-B family, respectively. We made several alignments employing different algorithms, namely with Blosum62, 120PAM or 3D-PSSM. We obtain altogether 10 models of the GnT-V structure.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů