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Transactivation by temperature-dependent p53 mutants in yeast and human cells

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00043807" target="_blank" >RIV/00216224:14310/10:00043807 - isvavai.cz</a>

  • Alternative codes found

    RIV/65269705:_____/10:#0001546

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Transactivation by temperature-dependent p53 mutants in yeast and human cells

  • Original language description

    We analyzed transactivation of several p53-target genes by 23 temperature-dependent p53 mutants and stratified them into four functional groups. Seventeen mutants exhibited temperature-dependency and discriminative character in human and yeast cells. Ouranalysis showed that functional analysis of separated alleles in yeast is valuable tool for assessment of the human p53 status.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NS10448" target="_blank" >NS10448: Detailed analyses of temperature-dependent mutants of the p53 tumor suppressor in human cells</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cell Cycle

  • ISSN

    1538-4101

  • e-ISSN

  • Volume of the periodical

    9

  • Issue of the periodical within the volume

    11

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

  • UT code for WoS article

  • EID of the result in the Scopus database