Spectroscopic study of protonation of cytosine-containing oligonucleotides

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00044422" target="_blank" >RIV/00216224:14310/10:00044422 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Spectroscopic study of protonation of cytosine-containing oligonucleotides
Original language description
Cytosine is an important building block of nucleic acids taking part in the process of genetic information transfer and transfer of energy of biologically important compounds by means of coenzymes. Due to acidobasic properties of bioligands, the presenceof protonated species is dependent on the protonation constants. It was also shown that oligonucleotides (ODNs) concerning cytosine can form the so called structural i motif as a consequence of probable stabilization of the secondary structure of biomacromolecules. The aim of this work was to determine the protonation constants of ODNs varying the number of bases in order to see their influence on thermodynamic stability of studied ligands.
Czech name
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Czech description
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Project
<a href="/en/project/LC06035" target="_blank" >LC06035: Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Sborníi 14. česko - slovenské spektroskopické konference
ISBN
978-80-7395-282-2
ISSN
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e-ISSN
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Number of pages
100
Pages from-to
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Publisher name
Spektroskopická společnost Jana Marka Marci
Place of publication
Pardubice
Event location
Litomyšl
Event date
May 31, 2010
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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