Evidence of synergistic toxicity in birds: experimental co-exposures to cyanobacteria and toxic metal (lead) causes immunosuppressions in Japanese quail

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00047662" target="_blank" >RIV/00216224:14310/10:00047662 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Evidence of synergistic toxicity in birds: experimental co-exposures to cyanobacteria and toxic metal (lead) causes immunosuppressions in Japanese quail
Original language description
Although the role of cyanobacterial metabolites in mass mortalities of wild birds has been discussed, there are only limited experimental data available on cyanobacterial toxicity in birds. The aim of the present study was to estimate the influence of cyanobacterial biomass, lead and immunological challenge in single and combined exposure scenarios on toxicity and biochemical responses in Japanese quail. The 30-day experiment was performed with 4 months old individuals divided into 8 groups. The presentexperimental study was successful in testing the hypothesis that adverse effects of cyanotoxins, heavy metals, and a non-pathogenic immunological challenge combine to enhance avian mortality. Moreover, single exposure to cyanobacterial biomass resultedin hepatic vacuolar dystrophy, while co-exposure with lead in a more severe granular dystrophy.
Czech name
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Czech description
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Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>O - Projekt operacniho programu

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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