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Use of 125I-labeled iodothyronines as tools for studies of Fluoxetine interaction with the metabolism of triiodothyronine

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00051577" target="_blank" >RIV/00216224:14310/10:00051577 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Use of 125I-labeled iodothyronines as tools for studies of Fluoxetine interaction with the metabolism of triiodothyronine

  • Original language description

    In studies of the interaction of an antidepressant drug fluoxetine with the metabolism of thyroid hormones in the rat, we applied adapted radiometric enzyme assays for iodothyronine sulfotransferases and uridine 5-diphospho-glucuronyltransferase, as wellas our newly developed radiometric assays for iodothyronine deiodinases of types 1, 2 and 3, using [I-125]-labeled iodothyronines as substrates.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů