125I-labelled iodothyronines: useful tools for studies of effects of an antidepressant drug fluoxetine in the rat
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00051563" target="_blank" >RIV/00216224:14310/10:00051563 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
125I-labelled iodothyronines: useful tools for studies of effects of an antidepressant drug fluoxetine in the rat
Original language description
We followed the effects of an antidepressant drug fluoxetine (Fluox), administered sub-chronically to Wistar rats by itself, or in combination with 3,3',5-triiodothyronine. In studies of the interaction of Fluox with the metabolism of thyroid hormones, we applied adapted radiometric enzyme assays for iodothyronine sulfotransferases and uridine 5'-diphospho-glucuronyltransferase, as well as our newly developed radiometric assays for iodothyronine deiodinases of types 1, 2 and 3, using 125I-labelled iodothyronines of high specific radioactivity as substrates.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Radioanalytical and Nuclear Chemistry
ISSN
0236-5731
e-ISSN
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Volume of the periodical
286
Issue of the periodical within the volume
3
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
5
Pages from-to
867-871
UT code for WoS article
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EID of the result in the Scopus database
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