Phosphoinositide 3-kinase inhibition enables retinoic acid-induced neurogenesis in monolayer culture of embryonic stem cells.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F12%3A00057219" target="_blank" >RIV/00216224:14310/12:00057219 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/12:10109075 RIV/49777513:23420/12:43914940
Result on the web
<a href="http://dx.doi.org/10.1002/jcb.23380" target="_blank" >http://dx.doi.org/10.1002/jcb.23380</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jcb.23380" target="_blank" >10.1002/jcb.23380</a>

Result language
angličtina
Original language name
Phosphoinositide 3-kinase inhibition enables retinoic acid-induced neurogenesis in monolayer culture of embryonic stem cells.
Original language description
Retinoic acid is able to induce the differentiation of embryonic stem cells into neuronal lineages. The mechanism of this effect is unknown but it has been evidenced to be dependent on the formation of floating spheroids called embryoid bodies. Results presented here show that the inhibition of phosphoinositide 3-kinase signaling predetermines mouse embryonic stem cells to retinoic acid induced neurogenesis in monolayer culture with no need of embryoid bodies formation.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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