Naphthalene-2,3-dicarbaldehyde derivatization of amino acids - an improved technique for minimization of benzoin condensation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F13%3A00066576" target="_blank" >RIV/00216224:14310/13:00066576 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Naphthalene-2,3-dicarbaldehyde derivatization of amino acids - an improved technique for minimization of benzoin condensation

Original language description

Amino acids (AA) have no native fluorescence thus chemical modification (so called derivatization) of AA has to be performed prior the detection by a fluorescent detector. There is a lot of derivatization reagents commercially available differing in reactivity, excitation and emission wavelengths, quantum yield, product stability etc. Naphtalene-2,3-dicarbaldehyde (NDA) is a non-fluorescent reagent giving fluorescent product of primary amines. Derivatization procedure is quite simple, however has to beoptimized to minimize undesired by-products of benzoin condensation. The by-products can exhibit fluorescence or form crystals which can clog capillary. The novel derivatization protocol using NDA for AA derivatization is subject of this contribution.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemické listy

ISSN

0009-2770

e-ISSN

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Volume of the periodical

107

Issue of the periodical within the volume

S3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

2

Pages from-to

"S351"-"S352"

UT code for WoS article

000328730800028

EID of the result in the Scopus database

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