Targeted proteomics of solid cancers: from quantification of known biomarkers towards reading the digital proteome maps

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00081233" target="_blank" >RIV/00216224:14310/15:00081233 - isvavai.cz</a>

Alternative codes found

RIV/00209805:_____/15:#0000650

Result on the web

<a href="http://dx.doi.org/10.1586/14789450.2015.1094381" target="_blank" >http://dx.doi.org/10.1586/14789450.2015.1094381</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1586/14789450.2015.1094381" target="_blank" >10.1586/14789450.2015.1094381</a>

Result language

angličtina

Original language name

Targeted proteomics of solid cancers: from quantification of known biomarkers towards reading the digital proteome maps

Original language description

The concept of personalized medicine includes novel protein biomarkers that are expected to improve the early detection, diagnosis and therapy monitoring of malignant diseases. Tissues, biofluids, cell lines and xenograft models are the common sources ofbiomarker candidates that require verification of clinical value in independent patient cohorts. Targeted proteomics ? based on selected reaction monitoring, or data extraction from data-independent acquisition based digital maps ? now represents a promising mass spectrometry alternative to immunochemical methods. To date, it has been successfully used in a high number of studies answering clinical questions on solid malignancies: breast, colorectal, prostate, ovarian, endometrial, pancreatic, hepatocellular, lung, bladder and others. It plays an important role in functional proteomic experiments that include studying the role of post-translational modifications in cancer progression.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Expert Review of Proteomics

ISSN

1478-9450

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

6

Country of publishing house

GB - UNITED KINGDOM

Number of pages

17

Pages from-to

651-667

UT code for WoS article

000364550700003

EID of the result in the Scopus database

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