Oral Fat Sensing and CD36 Gene Polymorphism in Algerian Lean and Obese Teenagers

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00085113" target="_blank" >RIV/00216224:14310/15:00085113 - isvavai.cz</a>
Alternative codes found
RIV/67985904:_____/15:00453677
Result on the web
<a href="http://dx.doi.org/10.3390/nu7115455" target="_blank" >http://dx.doi.org/10.3390/nu7115455</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/nu7115455" target="_blank" >10.3390/nu7115455</a>

Result language
angličtina
Original language name
Oral Fat Sensing and CD36 Gene Polymorphism in Algerian Lean and Obese Teenagers
Original language description
Growing number of evidences have suggested that oral fat sensing, mediated by a glycoprotein CD36 (cluster of differentiation 36), plays a significant role in the development of obesity. Indeed, a decreased expression of CD36 in some obese subjects is associated with high dietary fat intake. In the present study, we examined whether an increase in body mass index (BMI) is associated with altered oleic acid lingual detection thresholds and blood lipid profile in young Algerian teenagers (n = 165). The obese teenagers (n = 83; 14.01 ? 0.19 years; BMI z-score 2.67 ? 0.29) exhibited higher lingual detection threshold for oleic acid than lean participants (n = 82, 13.92 ? 0.23 years; BMI z-score 0.03 ? 0.0001). We also studied the association between rs1761667 polymorphism of CD36 gene and obesity. The AA and AG genotypes were more frequent in obese teenagers, whereas GG genotype was more common in lean participants. The A-allele frequency was higher in obese teenagers than that in lean chi
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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