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Conducting polyaniline based cell culture substrate for embryonic stem cells and embryoid bodies

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00087515" target="_blank" >RIV/00216224:14310/15:00087515 - isvavai.cz</a>

  • Alternative codes found

    RIV/61389013:_____/15:00444566 RIV/70883521:28610/15:43872986

  • Result on the web

    <a href="http://dx.doi.org/10.1039/C5RA07504A" target="_blank" >http://dx.doi.org/10.1039/C5RA07504A</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1039/C5RA07504A" target="_blank" >10.1039/C5RA07504A</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Conducting polyaniline based cell culture substrate for embryonic stem cells and embryoid bodies

  • Original language description

    In this work, thin films consisting of electrically conducting polyaniline (PANI) and poly(2-acrylamido-2-methyl-1-propanesulfonate) (PAMPSA) have been used as cell culture substrates for embryonic stem cells (ESC) and embryoid bodies (EMB). The PANI?PAMPSA films having fibrillar morphology were electrochemically polymerized in a single-step by cyclic voltammetry from an aqueous solution containing aniline and PAMPSA. UV-visible spectroscopy showed that the PANI films were electrically conducting stillat pH 10. This makes them suitable for tissue engineering applications operating at physiological pH, in contrast to the commonly used PANI hydrochloride films which loose their electrical conductivity at pH 4 and higher. Our results reveal that the PANI?PAMPSA films allow only for limited ESC adhesion and growth.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA13-08944S" target="_blank" >GA13-08944S: Interactions of Conducting Polymers with Cells.</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    RSC Advances

  • ISSN

    2046-2069

  • e-ISSN

  • Volume of the periodical

    5

  • Issue of the periodical within the volume

    62

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    50328-50335

  • UT code for WoS article

  • EID of the result in the Scopus database