Capillary Electrophoresis-Frontal Analysis For The Characterization Of Drug-Metal Binding

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00088254" target="_blank" >RIV/00216224:14310/16:00088254 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Capillary Electrophoresis-Frontal Analysis For The Characterization Of Drug-Metal Binding
Original language description
This study examined the possibilities of using capillary electrophoresis-frontal analysis (CE-FA) for the characterization of drug-metal binding parameters such as formation constant (Kf) and number of binding sites. Deferiprone and iron in the Fe(III) form were selected as model system. Apparent Kf values were obtained using nonlinear regression. The results provide a more quantitative picture of how this drug binds with metal and illustrate how CE FA can be used to examine drug metal interactions.
Czech name
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Czech description
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Project
<a href="/en/project/GBP206%2F12%2FG014" target="_blank" >GBP206/12/G014: Center for advanced bioanalytical technologies</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
13 th International Interdisciplinary Meeting on Bioanalysis CECE 2016
ISBN
9788090495944
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
197-199
Publisher name
Institute of Analytical Chemistry of the CAS, v. v. i., Brno, Czech Republic
Place of publication
Brno, Czech Republic
Event location
Brno, Czech Republic
Event date
Oct 17, 2016
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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