ROR1-based immunomagnetic protocol allows efficient separation of CLL and healthy B cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00088845" target="_blank" >RIV/00216224:14310/16:00088845 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/16:00066238
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1111/bjh.13848/epdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/bjh.13848/epdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/bjh.13848" target="_blank" >10.1111/bjh.13848</a>
Alternative languages
Result language
angličtina
Original language name
ROR1-based immunomagnetic protocol allows efficient separation of CLL and healthy B cells
Original language description
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia among adults in the Western world. This lymphoproliferative disorder is defined by the presence of at least 5 9 106 clonal lymphocytes/ml peripheral blood (Hallek,2015). The biggest clinical challenge is the fact that CLL eradication by any available therapy, apart from allogeneic stem cell transplantation, fails to cure the disease, inducing only temporary disease remission, i.e., when the disease does not manifest clinically but CLL cells still persist in the body. During this phase a population of CLL cells often slowly re-expands to trigger CLL relapse. The relapse is often based on the poorly understood but clinically important process of therapy-driven selection of more aggressive CLL subclones (Malcikova et al, 2015).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NV15-29793A" target="_blank" >NV15-29793A: Analysis of WNT/PCP pathway for better management of chronic lymphocytic leukemia</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
British Journal of Haematology
ISSN
0007-1048
e-ISSN
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Volume of the periodical
175
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
339-342
UT code for WoS article
000385763400019
EID of the result in the Scopus database
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