Identification of polycyclic aromatic hydrocarbons (PAHs) collected through passive air sampling and their effects in vitro on human pulmonary epithelial cell lines
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F25%3A00143927" target="_blank" >RIV/00216224:14310/25:00143927 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1080/10934529.2026.2613198" target="_blank" >https://doi.org/10.1080/10934529.2026.2613198</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/10934529.2026.2613198" target="_blank" >10.1080/10934529.2026.2613198</a>
Alternative languages
Result language
angličtina
Original language name
Identification of polycyclic aromatic hydrocarbons (PAHs) collected through passive air sampling and their effects in vitro on human pulmonary epithelial cell lines
Original language description
The presence of polycyclic aromatic hydrocarbons (PAHs) in ambient air is mainly linked to anthropogenic activities, particularly fossil fuel use and residential wood combustion, posing risks to human health. This study evaluated atmospheric PAHs in Temuco, Chile, characterized their spatial and seasonal distribution, and investigated the in vitro effects of environmentally relevant PAH mixtures on human bronchial epithelial cells (BEAS-2B). Passive air samplers equipped with polyurethane foam (PUF) disks were deployed at two urban sites (Universidad Católica de Temuco and Padre Las Casas) and one rural site (Maquehue sector). Sampling covered summer and fall–early winter, with seasonal assessment conducted in Padre Las Casas. PAHs were quantified by gas chromatography–mass spectrometry (GC–MS), and cell viability was assessed using the MTS assay after exposure to defined PAH mixtures. Spatial variability was observed, with phenanthrene, fluoranthene, and pyrene predominating in urban areas and increasing during winter, while dibenzo(a,h)anthracene was detected exclusively in the rural sector. In BEAS-2B cells, PAH exposure caused a dose and time-dependent reduction in viability, reaching significance at 20 and 28 μM after 48 and 72 h. These findings highlight PAH persistence and potential adverse effects on respiratory epithelial cells, underscoring the need to reduce population exposure.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10511 - Environmental sciences (social aspects to be 5.7)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING
ISSN
1093-4529
e-ISSN
1532-4117
Volume of the periodical
60
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
633-643
UT code for WoS article
001658765600001
EID of the result in the Scopus database
2-s2.0-105027979244