Calibration of Chiral Compounds with Self-Internal Standard. Application to Determination of S(-)-propranolol Hydrochloride by Capillary Zone Electrophoresis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F02%3A00007232" target="_blank" >RIV/00216224:14330/02:00007232 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Calibration of Chiral Compounds with Self-Internal Standard. Application to Determination of S(-)-propranolol Hydrochloride by Capillary Zone Electrophoresis

Original language description

A new method of calibration designed for chiral compounds named: Calibration with Self-internal Standard, is suggested. Here, the second enantiomer serves as the internal standard, the total concentration of both enantiomers is known and kept constant. The method is an alternative to the commonly used calibration with an internal standard being a chemically different compound. The applicability of the method is demonstrated on the calibration of propranolol hydrochloride in capillary zone electrophoresis. Statistical characteristics of the method are compared to calibration without an internal standard and with L-tryptophan as internal standard.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2002

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chromatographia

ISSN

0009-5893

e-ISSN

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Volume of the periodical

56

Issue of the periodical within the volume

9/10

Country of publishing house

DE - GERMANY

Number of pages

7

Pages from-to

597

UT code for WoS article

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EID of the result in the Scopus database

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