Automated spinning disk confocal microscopy in 3D live cell imaging

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F09%3A00036856" target="_blank" >RIV/00216224:14330/09:00036856 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14330/10:00043375
Result on the web
—
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Automated spinning disk confocal microscopy in 3D live cell imaging
Original language description
Fluorescence microscopy has become the leading technology to study structure and dynamics of cellular components and processes. The studies can be performed in two-dimensional (2D) but also in three-dimensional (3D) spatial coordinate system as well as in time and spectral dimensions. Fluorescent proteins allow us to study protein dynamics, localization, and interactions in living cells. In our laboratory, we have been developing special systems for automated cell image acquisition and analysis using fluorescence microscopy working up to five dimensions (x, y, z, t, lambda), whose hardware and software was optimized for studies on living cells. The presentation will focus on the latest developments in our technology. For the first time, we discovered interaction of apoptotic proteins AIF and endonuclease G, expressed using one DNA plasmid, in living human cells during apoptotic cell death.
Czech name
—
Czech description
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)