Model Checking Approach to the Analysis of Biological Systems
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F19%3A00107592" target="_blank" >RIV/00216224:14330/19:00107592 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-030-17297-8_1" target="_blank" >http://dx.doi.org/10.1007/978-3-030-17297-8_1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-030-17297-8_1" target="_blank" >10.1007/978-3-030-17297-8_1</a>
Alternative languages
Result language
angličtina
Original language name
Model Checking Approach to the Analysis of Biological Systems
Original language description
Formal verification techniques together with other computer science formal methods have been recently tailored for applications to biological and biomedical systems. In contrast to traditional simulation-based approaches, model checking opens an entirely novel way of viewing and analysing the dynamics of such systems. In particular, it can help in system identification and parameter synthesis, in comparison of models with respect to a priori given desired properties, in robustness analysis of systems, in relating models to experimental data, or in globally analysing the bifurcations of systems behaviour with respect to changes in parameters. In this review, we briefly describe the state-of-the-art methods and techniques employing model checking, as one of the most prominent verification techniques, to the analysis of biomedical systems. We demonstrate some of the advantages of using the model checking method by presenting a brief account of the technique itself followed by examples of the application of formal methods based on model checking to three areas related to the analysis of biomedical systems: verification of biological hypotheses, parameters synthesis, and bifurcation analysis. Finally, we discuss several case studies that show how fruitfully the methods can be utilised within the computational systems biology and biomedicine domain.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
—
OECD FORD branch
10600 - Biological sciences
Result continuities
Project
<a href="/en/project/GA18-00178S" target="_blank" >GA18-00178S: Discrete Bifurcation Analysis of Reactive Systems</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Automated Reasoning for Systems Biology and Medicine
ISBN
9783030172961
Number of pages of the result
33
Pages from-to
3-35
Number of pages of the book
474
Publisher name
Springer, Cham
Place of publication
Cham
UT code for WoS chapter
000503198000001