Chemoprotective effects of broccoli juice treated with high presssure

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14510%2F06%3A00031474" target="_blank" >RIV/00216224:14510/06:00031474 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Chemoprotective effects of broccoli juice treated with high presssure
Original language description
We investigated chemoprotective effects of broccoli juice, treated by high pressure method, using 500 MPa for a period of 10 minutes. By the use of this method, the conservation of nutritionally important substances occurs (for example vitamins, polyphenolic compounds, glucosinolates and other constituent substances). We followed the inhibition of mutagenicity of the model mutagen, N-nitroso-N-methylurea (MNU) by means of in vivo micronucleus test. After fourteen-days application of broccoli juice (0.2ml/10 g of body weight of mouse) and after single administration of MNU mutagen (50 mg/kg), a statistically significant decrease (p<0.01) occured, of number of micronuclei induced by the application of MNU. Broccoli juice treated by high pressure, therefore seems to have a preventive potential against MNU-induced micronuclei formation in BALB/C mouse bone marrow cells.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
GM - Food industry
OECD FORD branch
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Publication year
2006
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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