Broccoli juice treated by high presssure: chemoprotective effects of sulforaphane and indole-3-carbinol

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14510%2F07%3A00031920" target="_blank" >RIV/00216224:14510/07:00031920 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Broccoli juice treated by high presssure: chemoprotective effects of sulforaphane and indole-3-carbinol

Original language description

Numerous animal and epidemiological studies have demonstrated that consumption of cruciferous vegetables is inversely correlated with the cancer incidence. Using the shortterm mutagenicity test in vivo micronucleus test, we investigated inhibition of mutagenicity of IQ and MNU by influence of broccoli juice treated by high pressure method, 500 MPa for a period of 10 minutes. This technique of treatment suppresses the growth of microorganisms at simultaneous conservation of nutritionally important substances (vitamins, polyphenols, glucosinolates). We also investigated anticlastogenic aktivity of sulforaphane (SFN) and indol3carbinol (I3C). These two substances are found in inactive form (glucosinolates) in cruciferous vegetables Fourteendays application of broccoli juice and threedays application of I3C and SFN led to statistically significant inhibition of mutagenity.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2007

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

High pressure research

ISSN

0895-7959

e-ISSN

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Volume of the periodical

vol. 27

Issue of the periodical within the volume

n. 1

Country of publishing house

FR - FRANCE

Number of pages

6

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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