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Broccoli juice treated by high pressure, sulforaphane and indole-3-carbinol and their chemoprotective effects

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14510%2F06%3A00031595" target="_blank" >RIV/00216224:14510/06:00031595 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Broccoli juice treated by high pressure, sulforaphane and indole-3-carbinol and their chemoprotective effects

  • Original language description

    Numerous animal and epidemiological studies have demonstrated that consumption of cruciferous vegetables is inversely correlated with the cancer incidence. Using the shortterm mutagenicity test in vivo micronucleus test, we investigated inhibition of mutagenicity of IQ and MNU by influence of broccoli juice treated by high pressure method, 500 MPa for a period of 10 minutes. This technique of treatment suppresses the growth of microorganisms at simultaneous conservation of nutritionally important substances (vitamins, polyphenols, glucosinolates). We also investigated anticlastogenic aktivity of sulforaphane (SFN) and indol3carbinol (I3C). These two substances are found in inactive form (glucosinolates) in cruciferous vegetables Fourteendays application of broccoli juice and threedays application of I3C and SFN led to statistically significant inhibition of mutagenity.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Book of Abstracts and schedule, 44th EHPRG Meeting

  • ISBN

  • ISSN

    0895-7959

  • e-ISSN

  • Number of pages

    145

  • Pages from-to

  • Publisher name

    VUPP

  • Place of publication

    Praha

  • Event location

    Praha

  • Event date

    Sep 4, 2006

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article