MicroRNAs Biogenesis, Function and Decay

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00060169" target="_blank" >RIV/00216224:14740/12:00060169 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
MicroRNAs Biogenesis, Function and Decay
Original language description
MicroRNAs (miRNAs) are important regulators of gene expression that control both physiological and pathological processes such as development and cancer. Research during the past decade has identified major factors participating in miRNA biogenesis and has established basic principles of miRNA function. Recent studies, however, have introduced a paradigm shift in our understanding of the miRNA biogenesis pathway, which was previously believed to be universal to all miRNAs. It has become apparent that miRNA regulators themselves are subject to sophisticated control, which takes place at the levels of both miRNA metabolism and function. In this chapter we focus on the recent advances in knowledge of the miRNA biogenesis pathways and regulatory mechanismsinvolved in miRNA gene transcription, processing, maturation and functionality. Potential impact of the alterations in miRNA biogenesis pathways on cancer pathogenesis is discussed.
Czech name
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Czech description
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Project
<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets
ISBN
9781613245149
Number of pages of the result
20
Pages from-to
1-20
Number of pages of the book
192
Publisher name
Nova Science Publishers, Inc.
Place of publication
New York
UT code for WoS chapter
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