Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00064605" target="_blank" >RIV/00216224:14740/12:00064605 - isvavai.cz</a>

Result on the web

<a href="http://www.karger.com/Article/Abstract/334765" target="_blank" >http://www.karger.com/Article/Abstract/334765</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000334765" target="_blank" >10.1159/000334765</a>

Result language

angličtina

Original language name

Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia

Original language description

Aims: Using fMRI, we evaluated the default mode network (DMN) and the extrastriate visual resting state network (ESV-RSN) in 14 patients with Parkinson's disease dementia (PDD) as compared with 18 patients with Parkinson's disease (PD) without dementia and 18 healthy controls (HC). Methods: We analyzed the seed-based functional connectivity of both resting state data and deactivations during a visual complex scene-encoding task. Results: Using the posterior cingulate cortex/precuneus as a seed for the DMN analysis, we observed significant decreases of connectivity in the right inferior frontal gyrus in PDD as compared to PD and HC. Using the caudate nucleus as a seed for the ESV-RSN analysis, we found significant decreases of connectivity in the left and right inferior occipital gyrus in PDD as compared to HC. Conclusion: Differences in functional connectivity patterns between PDD and PD/HC were observed in areas known to be engaged in stimulus-driven reorienting of attention and in vi

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

—

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neurodegenerative Diseases

ISSN

1660-2854

e-ISSN

—

Volume of the periodical

10

Issue of the periodical within the volume

1-4

Country of publishing house

CH - SWITZERLAND

Number of pages

6

Pages from-to

232-237

UT code for WoS article

000303660600049

EID of the result in the Scopus database

—