The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00064606" target="_blank" >RIV/00216224:14740/12:00064606 - isvavai.cz</a>
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pubmed/22002597" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/22002597</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00702-011-0723-5" target="_blank" >10.1007/s00702-011-0723-5</a>
Alternative languages
Result language
angličtina
Original language name
The default mode network integrity in patients with Parkinson's disease is levodopa equivalent dose-dependent
Original language description
Disturbances in the default mode network (DMN) have been described in many neurological and psychiatric disorders including Parkinson's disease (PD). The DMN is characterized by basal activity that increases during rest or passive visual fixation and decreases ("deactivates'') during cognitive tasks. The network is believed to be involved in cognitive processes. We examined the DMN in PD patients on dopaminergic medication with normal cognitive performance compared to age-and gender-matched healthy controls (HC) using fMRI and three methodological procedures: independent component analysis of resting-state data, analysis of deactivation during a complex visual scene-encoding task, and seed-based functional connectivity analysis. In the PD group, we also studied the effect of dopaminergic medication on the DMN integrity.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Neural Transmission
ISSN
0300-9564
e-ISSN
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Volume of the periodical
119
Issue of the periodical within the volume
4
Country of publishing house
AT - AUSTRIA
Number of pages
12
Pages from-to
443-454
UT code for WoS article
000302423900005
EID of the result in the Scopus database
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