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Functional anatomy of outcome evaluation during Iowa Gambling Task performance in patients with Parkinson's disease: an fMRI study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F13%3A00068514" target="_blank" >RIV/00216224:14740/13:00068514 - isvavai.cz</a>

  • Alternative codes found

    RIV/68081740:_____/13:00420755

  • Result on the web

    <a href="http://link.springer.com/content/pdf/10.1007%2Fs10072-013-1439-0.pdf" target="_blank" >http://link.springer.com/content/pdf/10.1007%2Fs10072-013-1439-0.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s10072-013-1439-0" target="_blank" >10.1007/s10072-013-1439-0</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Functional anatomy of outcome evaluation during Iowa Gambling Task performance in patients with Parkinson's disease: an fMRI study

  • Original language description

    The aim of this study was to investigate the functional anatomy of decision-making during the Iowa Gambling Task in patients with Parkinson's disease. We used event-related functional magnetic resonance imaging (fMRI) during a computerized version of IGTto compare 18 PD patients on dopaminergic medication in the ON state and 18 healthy control subjects. Our analyses focused on outcome evaluation following card selection, because we expected this aspect of decision-making to be impaired in PD patients.The PD patients exhibited lower activation of the left putamen than the control group as a reaction to penalty. Using psychophysiological interaction analysis, we identified decreased functional connectivity between the right globus pallidus internus andthe left anterior cingulate gyrus in the PD group. In contrast, increased connectivity between these structures was observed after penalty in the control group.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    NEUROLOGICAL SCIENCES

  • ISSN

    1590-1874

  • e-ISSN

  • Volume of the periodical

    34

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    2159-2166

  • UT code for WoS article

    000328209500011

  • EID of the result in the Scopus database