Quadruplex-forming sequences occupy discrete regions inside plant LTR retrotransposons

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F14%3A00074769" target="_blank" >RIV/00216224:14740/14:00074769 - isvavai.cz</a>

Alternative codes found

RIV/68081707:_____/14:00436687 RIV/68081707:_____/14:00440128

Result on the web

<a href="http://nar.oxfordjournals.org/content/early/2013/10/07/nar.gkt893" target="_blank" >http://nar.oxfordjournals.org/content/early/2013/10/07/nar.gkt893</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/nar/gkt893" target="_blank" >10.1093/nar/gkt893</a>

Result language

angličtina

Original language name

Quadruplex-forming sequences occupy discrete regions inside plant LTR retrotransposons

Original language description

Retrotransposons with long terminal repeats (LTR) form a significant proportion of eukaryotic genomes, especially in plants. They have gag and pol genes and several regulatory regions necessary for transcription and reverse transcription. We searched forpotential quadruplex-forming sequences (PQSs) and potential triplex forming sequences (PTSs) in 18 377 full-length LTR retrotransposons collected from 21 plant species. We found that PQSs were often located in LTRs, both upstream and downstream of promoters from which the whole retrotransposon is transcribed. Upstream-located guanine PQSs were dominant in the minus DNA strand, whereas downstream-located guanine PQSs prevailed in the plus strand, indicating their role both at transcriptional and post-transcriptional levels. Our circular dichroism spectroscopy measurements confirmed that these PQSs readily adopted guanine quadruplex structures - some of them were paralell-stranded, while others were anti-parallel-stranded.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nucleic Acids Research

ISSN

0305-1048

e-ISSN

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Volume of the periodical

42

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

968-978

UT code for WoS article

000331138100030

EID of the result in the Scopus database

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