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Monitoring Progress of Parkinson's Disease Based on Changes in Phonation: a Pilot Study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F18%3A00108633" target="_blank" >RIV/00216224:14740/18:00108633 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216305:26220/18:PU128446

  • Result on the web

    <a href="http://dx.doi.org/10.1109/TSP.2018.8441307" target="_blank" >http://dx.doi.org/10.1109/TSP.2018.8441307</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1109/TSP.2018.8441307" target="_blank" >10.1109/TSP.2018.8441307</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Monitoring Progress of Parkinson's Disease Based on Changes in Phonation: a Pilot Study

  • Original language description

    Hypokinetic dysarthria (HD) is a frequent symptom of idiopathic Parkinson's disease (PD). Although it is hypothesized its progress is tightly linked with changes in other motor/non-motor features of PD, it has not been proved yet. The aim of this work is to employ acoustic analysis of sustained phonation in order to identify significant correlates between phonatory measures and motor/non-motor deficits in a two-year follow-up study. For this purpose, we repeatedly quantified a sustained vowel /a/ in 51 PD patients who were also assessed by 5 common clinical scales. In addition, a multivariate regression model was trained to predict the motor/non-motor deficits in the horizon of two years. Results suggest that mainly instability in vocal folds oscillation increases with the progress of PD and with overall cognitive decline. Based on the acoustic analysis, the change in clinical scores could be predicted with the error in the range of 11.83-19.60 %.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

    <a href="/en/project/NV16-30805A" target="_blank" >NV16-30805A: Effects of non-invasive brain stimulation on hypokinetic dysarthria, micrographia, and brain plasticity in patients with Parkinson's disease</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    2018 41ST INTERNATIONAL CONFERENCE ON TELECOMMUNICATIONS AND SIGNAL PROCESSING (TSP)

  • ISBN

    9781538646953

  • ISSN

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

    218-221

  • Publisher name

    IEEE

  • Place of publication

    NEW YORK

  • Event location

    Athens, GREECE

  • Event date

    Jul 4, 2018

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article

    000454845100051