Monitoring Progress of Parkinson’s Disease Based on Changes in Phonation: a Pilot Study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F18%3APU128446" target="_blank" >RIV/00216305:26220/18:PU128446 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/18:00108633
Result on the web
<a href="https://ieeexplore.ieee.org/document/8441307" target="_blank" >https://ieeexplore.ieee.org/document/8441307</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1109/TSP.2018.8441307" target="_blank" >10.1109/TSP.2018.8441307</a>

Result language
angličtina
Original language name
Monitoring Progress of Parkinson’s Disease Based on Changes in Phonation: a Pilot Study
Original language description
Hypokinetic dysarthria (HD) is a frequent symptom of idiopathic Parkinson’s disease (PD). Although it is hypothesized its progress is tightly linked with changes in other motor/non-motor features of PD, it has not been proved yet. The aim of this work is to employ acoustic analysis of sustained phonation in order to identify significant correlates between phonatory measures and motor/non-motor deficits in a two-year follow-up study. For this purpose, we repeatedly quantified a sustained vowel /a/ in 51 PD patients who were also assessed by 5 common clinical scales. In addition, a multivariate regression model was trained to predict the motor/non-motor deficits in the horizon of two years. Results suggest that mainly instability in vocal folds oscillation increases with the progress of PD and with overall cognitive decline. Based on the acoustic analysis, the change in clinical scores could be predicted with the error in the range of 11.83–19.60 %.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
41st International Conference on Telecommunications and Signal Processing (TSP)
ISBN
978-1-5386-4695-3
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
218-221
Publisher name
Institute of Electrical and Electronics Engineers Inc.
Place of publication
Atény, Řecko
Event location
Athens, Greece
Event date
Jul 4, 2018
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000454845100051

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