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Interplays of different types of epitranscriptomic mRNA modifications

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F21%3A00124288" target="_blank" >RIV/00216224:14740/21:00124288 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.tandfonline.com/doi/full/10.1080/15476286.2021.1969113" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/15476286.2021.1969113</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/15476286.2021.1969113" target="_blank" >10.1080/15476286.2021.1969113</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Interplays of different types of epitranscriptomic mRNA modifications

  • Original language description

    Eukaryotic mRNAs are modified by several chemical marks which have significant impacts on mRNA biology, gene expression, and cellular metabolism as well as on the survival and development of the whole organism. The most abundant and well-studied mRNA base modifications are m(6)A and ADAR RNA editing. Recent studies have also identified additional mRNA marks such as m(6)Am, m(5)C, m(1)A and psi and studied their roles. Each type of modification is deposited by a specific writer, many types of modification are recognized and interpreted by several different readers and some types of modifications can be removed by eraser enzymes. Several works have addressed the functional relationships between some of the modifications. In this review we provide an overview on the current status of research on the different types of mRNA modifications and about the crosstalk between different marks and its functional consequences.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    <a href="/en/project/LTC18052" target="_blank" >LTC18052: Integrative studies of molecular mechanisms of mammalian epitranscriptome</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    RNA Biology

  • ISSN

    1547-6286

  • e-ISSN

  • Volume of the periodical

    18

  • Issue of the periodical within the volume

    S1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    12

  • Pages from-to

    19-30

  • UT code for WoS article

    000687601700001

  • EID of the result in the Scopus database

    2-s2.0-85113759012