Dual Hydrophilic Interaction-RP Retention Mechanism on Polar Columns: Structural Correlations and Implementation for 2-D Separations on a Single Column

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F10%3A39882372" target="_blank" >RIV/00216275:25310/10:39882372 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Dual Hydrophilic Interaction-RP Retention Mechanism on Polar Columns: Structural Correlations and Implementation for 2-D Separations on a Single Column

Original language description

We investigated the retention of phenolic acid and flavone antioxidants on five polar columns in buffered aqueous ACN mobile phases. All columns show mixed retention mechanism: RP in highly aqueous mobile phases and normal phase (hydrophilic interactionLC, HILIC) in mobile phases with high concentration of ACN. The Silica Hydride and the ZIC HILIC sulfobetaine zwitterionic columns show rather limited retention in the RP mode. The Luna HILIC column shows higher retention in both the HILIC and the RP modes in comparison to the PEG and DIOL columns. We characterized the selektivity of various HILIC systems using linear solvation energy relationship model with molecular structure descriptors characterizing selective molecular size, dipole-dipole and proton- donor/proton-acceptor interactions and we investigated the effects of the mobile phase composition on the linear solvation energy relationship characteristics of the separation phase.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

<a href="/en/project/GA203%2F07%2F0641" target="_blank" >GA203/07/0641: New analytical methods in combined high-capacity phase separation systems</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Separation Science

ISSN

1615-9306

e-ISSN

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Volume of the periodical

33

Issue of the periodical within the volume

6-7

Country of publishing house

DE - GERMANY

Number of pages

12

Pages from-to

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UT code for WoS article

000276782700018

EID of the result in the Scopus database

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