Cross-Linker Effects on the Separation Efficiency on (Poly)methacrylate Capillary Monolithic Columns. Part II. Aqueous Normal-Phase Liquid Chromatography

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F13%3A39896311" target="_blank" >RIV/00216275:25310/13:39896311 - isvavai.cz</a>
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0021967313004639" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0021967313004639</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.chroma.2013.03.025" target="_blank" >10.1016/j.chroma.2013.03.025</a>

Result language
angličtina
Original language name
Cross-Linker Effects on the Separation Efficiency on (Poly)methacrylate Capillary Monolithic Columns. Part II. Aqueous Normal-Phase Liquid Chromatography
Original language description
We synthesized seven different polymethacrylate monolithic capillary columns using N,N-dimethyl-N-metacryloxyethyl-N-(3-sulfopropyl) ammonium betaine functional monomer (MEDSA) and various cross-linking monomers differing in the polarity and size. The efficiency of monolithic columns for polar low-molecular compounds in the aqueous normal-phase (HILIC) mode depends rather on the polarity, than on the size of the cross-linker molecules. Cross-linking molecules, which exhibit high polarity can produce poly(methacrylate) monoliths with an increase in pore sizes below 50 nm. Columns prepared with pentaerythritol triacrylate or bisphenol A dimethacrylate cross-linkers show large inner pore (mesopore) porosity, and provide poor efficiency, whereas columns with trioxyethylene dimethacrylate (TriEDMA) and tetraoxyethylene dimethacrylate (TeEDMA) cross-linkers showed poor permeability. Columns prepared using dioxyethylene dimethacrylate (DiEDMA), and especially glycerolate dimethacrylate (BIGDM
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Project
<a href="/en/project/GAP206%2F12%2F0398" target="_blank" >GAP206/12/0398: Two-dimensional separations in liquid media</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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