LC/MS and SFC/MS in Lipidomic Analysis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F14%3A39899346" target="_blank" >RIV/00216275:25310/14:39899346 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
LC/MS and SFC/MS in Lipidomic Analysis
Original language description
Lipidomic analysis is challenging due to enormous complexity of lipid structures. The mass spectrometry (MS) plays a key role in the quantitative lipidomics either without separation (shotgun ESI-MS or MALDI-TOF) or in separation coupling with MS (mainlyLC/MS and SFC/MS). Each modality can bring complementary information, which can be integrated in one overall methodology. Various quantitative LC/MS and SFC/MS approaches will be discussed as well. The goal of this work is the development of complementary nontargeted and targeted MS based method for the comprehensive characterization of biological samples, which is applied for the characterization of changes caused by the tumor growth in comparison with surrounding healthy tissues.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LL1302" target="_blank" >LL1302: Mass Spectrometry in Cancer Research: Lipid Biomarkers for Early Diagnostics</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů