Compressibility of tableting materials and properties of tablets with glyceryl behenate

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F15%3A39899505" target="_blank" >RIV/00216275:25310/15:39899505 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11160/15:10312215
Result on the web
<a href="http://dx.doi.org/10.1515/acph-2015-0006" target="_blank" >http://dx.doi.org/10.1515/acph-2015-0006</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1515/acph-2015-0006" target="_blank" >10.1515/acph-2015-0006</a>

Result language
angličtina
Original language name
Compressibility of tableting materials and properties of tablets with glyceryl behenate
Original language description
The paper studies the compressibility of directly compressible tableting materials with dry binders, spray-dried lactose and microcrystalline cellulose, and glyceryl dibehenate at various concentrations. Compressibility was evaluated by means of the energy profile of compression and tensile strength of tablets. Release rate of the active ingredient, salicylic acid, from the tablets was also examined. In the case of microcrystalline cellulose, a higher concentration of glyceryl dibehenate increased the strength of tablets, while this did not occur in the case of spray-dried lactose. Increasing concentration of glyceryl dibehenate prolonged the release of salicylic acid; however, no statistically significant difference was found compared to the type of the dry binder used.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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